Put it right after the winning moment in your edit, then follow it with Emotional Damage for the losing side to complete the contrast. If you want a different reaction first, open with the Bruh Sound Effect before the laugh takes over.
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This nearly seven-second clip is Amelia Watson doing the ojou-sama laugh, a high, posh ohohoho that climbs as she repeats it. It feels gleefully smug and theatrical, like a cartoon heiress celebrating a victory she never doubted. She performed it on stream as a Hololive English VTuber, and fans clipped it for reaction videos and meme edits.