End a short confession clip with it, then follow it with Oh Brother This Guy Stinks for the reaction and Ba Dum Tss to close the beat. Keep it as the punchline rather than the opener, so the admission sets it up and the follow-up sounds carry the joke forward.
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This is a short spoken clip of Joe Biden saying the line 'my butt's been wiped' in a flat, matter-of-fact delivery, lasting just over a second. The blunt, childlike phrasing lands as awkward and funny, especially because it sounds so earnest coming from a former president. It works best as a quick, deadpan reaction to an embarrassing or overly personal admission.