Place it at the end of an exchange, after a shocked reaction and before any laugh, so it closes the moment instead of opening another one. Pair it with the shocked meme sound for the setup, then follow with the goofy yell if the scene needs to escalate again.
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This is a short vocal clip built around a single blunt 'heuh', lasting just under three seconds. The flat, thrown-off delivery lands as a dry, awkward reaction, somewhere between a laugh, a grunt and a shrug, and it works because it sounds deliberately unimpressed. It gives a listener a quick jolt of comic dismissal without saying anything more.