Place it at the end of a build-up, right before the visual payoff, then follow the impact with a bruh reaction and a quick scream meme stinger to close the sequence without extra commentary or effects layered underneath.
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A very short voice clip, just over a second long, of Mr Krupp shouting the warning phrase fire in the hole at full volume. The delivery is abrupt and over-serious, which makes the moment feel funny and oddly tense at the same time, like a tiny emergency announced for something completely trivial and about to go wrong.