Place it at the end of a funny moment, just after the punchline, so it closes the joke. Follow it with Nelson's Ha-Ha! for a second reaction, or use the Laughing Dog Meme instead when the humour comes from a pet.
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This is a short 1.8-second burst of human laughter, one clear laugh meant for quick reactions. It feels light, cheeky and instantly contagious, the kind of laugh that makes a silly moment feel even funnier without needing any words at all.