Spider-Man has long been a shorthand for dramatic heroics in comics, cartoons and films, which is why a panicked scream in his voice works so well as a meme. The clip circulates mainly as a short reaction sound on soundboards and in short-form video edits, where creators use it to punctuate failure, embarrassment and unexpected bad news. Because the character is instantly recognisable and the emotion is unmistakable even without context, the sound stays useful across gaming, commentary and comedy videos years after it first began circulating online.