Place it just after the gross or cringe reveal in an edit, following Eww Brother Eww for the first reaction and then letting Oh My God Wow close the sequence, so the second beat lands after the first.
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This clip is an 11-second drawn-out vocal groan, repeated as a low, weary 'ugh' that drags on with clear frustration in the voice. It feels instantly exasperated and disgusted, like a sigh stretched into a complaint, and it lands as a comic overreaction to something gross, cringe or deeply annoying.