Brother Eww has circulated as a short reaction clip on soundboards and in short-form videos, where creators reuse it whenever a moment calls for instant disgust. Its exact original video is not widely documented, so its popularity comes from how reusable it is rather than a single famous scene. Like other blunt reaction sounds, it works as shorthand for gross-out humour, often appearing alongside other meme reactions such as a bruh reaction in edits that pile on disbelief and disgust. That flexibility keeps it in rotation for fails, food videos and awkward skits.