Place it at the end of a scene, after the setback has landed and before the next scene begins, so it closes the exchange. Pair it first with a reaction of disbelief, then let this acceptance follow, and finish with a light laugh to keep the sequence moving.
Über diesen Sound
This is a short Portuguese line from Futurama, lasting about 1.6 seconds, in which a character calmly accepts a situation with the words “Então tudo bem.” It feels resigned and lightly humorous, like giving in without making a fuss, and it works as a deadpan shrug in conversation.