The line comes from The Simpsons episode Selma's Choice from 1993, where Lisa becomes intoxicated after drinking the water on a Duff Gardens ride. In her hallucination she proudly announces herself as the Lizard Queen, a moment that became one of Lisa's most quoted outbursts. Clips and screenshots circulated on forums and meme pages for years, and the short audio later spread as a reaction sound on soundboards and in edits, usually detached completely from the original amusement park scene.