Place it as the closing reaction after the setup line in your edit, then follow the laugh beat with a hell naw dog cutaway before you roll into a we do not care button as the dismissive sign-off for the scene.
Über diesen Sound
This clip is a spoken voice line lasting about eleven seconds, built around the exaggerated phrase in its title delivered with dramatic emphasis. It feels funny and awkward at once, the kind of overblown frustration that lands as a joke rather than a serious threat, which is why listeners treat it as a meme reaction.