Place it at the end of a reaction sequence, after a setup line and just before the visual payoff, then follow it with a Bruh sound for a second reaction or a Meme sound when the edit needs one more laugh.
Über diesen Sound
ItmeJP 5 is a 1.6-second meme sound, brief enough to pass in a single breath of a quick conversation. It feels abrupt and playful, a tiny jolt that makes a chat pause for a beat, smile, and then move on again.