Place it as the payoff at the end of a setup, right after the bad suggestion is shown, then follow it with the No No Wait Wait sound for a second protest or the Wrong Answer Game Show sound to underline the mistake.
Über diesen Sound
This is a very short clip of comedian John Mulaney shouting a single, emphatic “No!” in under a second. The delivery is loud, abrupt and deliberately over-the-top, turning a simple refusal into a punchline. It feels funny, exasperated and instantly dismissive, like shutting down a bad idea before it gets any further.