Put it at the end of the setup, right as the choice is made, then follow the fallout with the Vine Boom Sound Effect for impact and, for a slower reveal, let the Dramatic Dun Dun Dun Sound Effect lead into it instead.
Über diesen Sound
This is a longer red-button press effect, lasting just under three seconds, built around a deep mechanical press and a rising warning tone rather than a single click. It feels dramatic and uneasy, like a decision has gone too far to take back, which makes a joke choice feel far bigger than it is.