Place it just before the reaction shot in a food or classroom edit, then follow it with a bruh soundboard button for the disbelief and a game show buzzer sound button when the answer finally gets rejected.
Über diesen Sound
This short clip is a male voice asking in Spanish 'La mayonesa es un instrumento?' in about two and a half seconds. The earnest, completely serious delivery makes a ridiculous question feel important, which is why listeners find it funny, awkward and instantly quotable for dumb questions.