Place it near the start of a reaction sequence, right after the strange claim appears, then follow it with Bruh for a second reaction and Emotional Damage when the moment turns into a full roast. Keep the sequence short so the name stays the punchline.
Über diesen Sound
This is a very short spoken clip built around the single word Sacowea, delivered in a blunt, off-kilter style that feels deliberately strange. It gives a quick jolt of confused amusement, like catching someone mid-nonsense and not knowing whether to laugh or stare. Its odd delivery makes it work best as a sudden, deadpan reaction rather than a warm greeting.