The line comes from Resident Evil 4, first released in 2005, where the Ganados, the infected villagers who hunt Leon S. Kennedy through rural Spain, shout threats as they attack in groups. Its blunt Spanish wording and furious delivery made it stand out from other enemy dialogue, and players began clipping it for reaction videos, horror edits and Spanish-language memes. It remains popular because it is short, instantly aggressive and easy to recognise, even for viewers who have never played the game, giving creators a ready-made warning before chaos begins.