Place it between a stopped riff and the next full-band entry in your edit, as a bridge rather than a punchline. Pair it first with a low drum hit, then follow it with a heavier guitar or bass sound for contrast.
Über diesen Sound
This clip is a very short whale noise effect lasting under a second, made with a guitar in the style of Gojira rather than a real animal recording. It feels eerie and mournful, like a distant ocean call cutting through heaviness. It comes from Nik Nocturnal's short 'How to Gojira in 30 Seconds' tutorial.