The sound is associated with Dr. Zoidberg from the animated TV series Futurama, where the character’s odd movements and panicked energy made the woop-style vocal memorable. It spread online through clips, reaction edits, and short meme compilations, especially when creators needed a quick audio cue for an absurd escape or embarrassed retreat. Its staying power comes from how instantly it signals weirdness and comedy without needing any setup, much like other cartoon reaction sounds such as Spongebob disappointed.