The line comes from Beavis, one half of the duo in Beavis and Butt-Head, the MTV animated series created by Mike Judge that premiered in 1993. Beavis was known for his nasal voice, low intelligence, and blank responses to almost everything. Short voice clips from the show spread widely on soundboards and in meme edits during the 2000s and 2010s. This particular shrug of an answer survived because it fits any clueless moment online, long after the original episode context was forgotten.
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A short clip of Beavis saying I don't know in his goofy voice, used as a clueless reaction sound for dumb questions and confusion in meme videos.
This short clip captures Beavis delivering a flat, nasal I don't know in his unmistakable slurred drawl. It is just over a second long, with no setup or punchline, which makes the blankness funnier. The voice sounds genuinely lost, like his brain has completely checked out mid-conversation. Viewers instantly recognize the dumb, spaced-out energy and use it to puncture any serious moment. It works because the delivery is so honest and empty that it turns confusion into the joke itself, rather than just admitting a lack of knowledge.