Place it as the payoff at the end of a help or rescue sequence, after the problem has been shown clearly. Pair it with a record scratch before it for a sudden turn, or follow it with applause for a bigger finish.
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This clip is a single stretched shout of gracias, held for about two seconds in a loud, theatrical voice. It turns a plain thank you into a big, funny outburst that feels grateful and over the top at the same time. The upload credits Multimedios, the Mexican television network.