Mama Luigi comes from the Super Mario World animated series produced by DiC in 1991, where Baby Yoshi calls Luigi Mama Luigi in the episode of the same name. The nickname and Luigi's stressed delivery became a lasting joke among Mario fans and later resurfaced in YouTube Poops and meme edits. This isolated yell is now shared as a scream meme, reused whenever a clip needs an instantly recognisable cartoon panic reaction from Nintendo's most nervous brother.