Place it immediately after the repeated interruption is shown, so the reaction answers the setup, then follow it with Eww Brother Eww to extend the rejection before cutting to the next scene, keeping that exchange as the short centre of the edit.
Sobre este sonido
This three-second voice clip delivers the line 'U bother me all the time' in a blunt, fed-up tone, with the emphasis landing hard on the complaint itself. It feels exasperated and playfully confrontational, like a quick eye-roll in audio form, made for shutting down a joke that has gone on one message too long.