La mardita gente comes from everyday Maracucho speech in Maracaibo, Venezuela, where coño e su madre is a common emphatic curse and mardita is a local pronunciation of maldita. Clips like this spread mainly as short WhatsApp audios and reaction sounds shared among Venezuelan users, then into wider Latin American meme edits. Its appeal is the specific regional accent and over the top frustration, which turns a generic complaint about people into a recognisable character moment that Venezuelans abroad also use to signal home.