The Binding of Isaac was released in 2011 by Edmund McMillen and Florian Himsl and later expanded in the 2014 remake Rebirth, where the Mulligan remained a familiar early enemy. The enemy is designed as a swollen, tearful double of Isaac that avoids direct contact and leaves flies behind when it dies. As Isaac clips, challenge runs and fail compilations spread on YouTube and Twitch, players began isolating short enemy cries like this one for soundboards and edits, where it now works as shorthand for a miserable, doomed character.