The line comes from Stanley Hudson, the deadpan salesman played by Leslie David Baker in the American version of The Office, which ran on NBC from 2005 to 2013. Stanley's blunt, unimpressed delivery made many of his short reactions ideal for isolating as clips, and this one spread through meme edits, reaction videos and soundboards. Editors pair it with other office style reactions, but its plain exasperated question keeps it usable far beyond fans of the show, which is why it still circulates as a universal response to nonsense.