Stimpaks are the main healing item in Fallout 4, the 2015 post-apocalyptic role-playing game from Bethesda, and the injection sound is heard whenever a player or companion uses one. The clip has circulated through gameplay videos, livestreams and game soundboards, where fans reuse it outside the game to signal healing, recovery or a second chance. Its staying power comes from that clear association: even without the visuals, listeners who know Fallout immediately connect the hiss and click with restoring health in the wasteland.