Gamw thn panagia is the Romanised spelling of the Greek phrase γαμώ την Παναγία, one of the most offensive profanities in everyday Greek speech. Panagia refers to the Virgin Mary, a central figure in Greek Orthodox culture, which explains the phrase's strong taboo status. The expression has long been used as an extreme curse for anger or pain, and online it spread through Greek forums, gaming chats and soundboards as a short reaction clip detached from any single film or show.