Rain World is a 2017 survival platform game in which players guide a slugcat through a harsh, rain-soaked world filled with predators, including several kinds of lizards that hunt by sight and sound. A lizard hiss in the game signals aggression or alarm, warning players that danger is close, which is why the short clip is easy to recognise out of context. Shared on soundboards and reused in gaming edits, it has become a handy shorthand for a reptile threat, a tense encounter, or a creature lurking just out of view.