Resident Evil 4, released in 2005, follows Leon S. Kennedy on a rescue mission in rural Spain, and herbs are the series' classic healing items, collected and combined to restore health. The short herb cue belongs to that item system, so players associate it with survival, preparation and recovery rather than combat. As Resident Evil 4 was re-released and remade, clips of its sounds continued to circulate among fans, and editors now reuse the herb sound as a compact shorthand for healing in gaming videos and memes.