Place it right after the moment of failure in a short edit, then follow it with the Nope Meme Sound Button for a firm refusal, or open with the Run Vine Sound Button to build momentum before the reaction lands.
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This short clip repeats the exclamation aduh duh duh duh in a rising, flustered voice that sounds caught between a groan and a laugh. It carries a feeling of comic exasperation, the sound of someone watching a small disaster unfold and having no better response. It comes from Once Upon a Time in Hollywood, where the line lands as a brief burst of disbelief.