Place it right after the on-screen question in a reaction edit, then let the next clip carry the consequence. Pair it before a bruh effect for a second shrug, or follow it with a laugh track when the group reacts to the non-answer.
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A short voice clip of a man saying he does not know, calling the other person brother, then trailing into a long drawn out oohhh. It lasts about five seconds and lands as a clueless shrug in sound form. The feeling is awkward and funny, like being caught without an answer and stretching the moment instead of explaining anything at all.