Grand Theft Auto V launched in 2013 from Rockstar Games and its Los Santos pedestrians have become a meme staple thanks to their dramatic reactions to player mayhem. Clips of NPCs fleeing crashes and explosions spread through YouTube compilations, Discord soundboards and TikTok edits, where the scream works as shorthand for total chaos. Fans pair it with other Los Santos clips like the GTA V notification for full roleplay edits. Years later the reaction still lands because almost every player recognises that instant panic.