The phrase is a Portuguese League of Legends callout meaning there is a Vayne here, and the clip is associated with the name FakeMito. Vayne has a long reputation as a terrifying late game marksman who can melt tanks and duel almost anyone, so spotting her changes a match instantly. Brazilian players shared the panicked shout as a reaction sound, and it spread through gameplay edits and soundboards as shorthand for danger arriving. It stays popular because the fear is specific to Vayne but the reaction works for any sudden threat.
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A panicked Portuguese shout warning that Vayne is here from League of Legends, used as a meme alert in gameplay clips, streams and funny edits.
This clip captures a player suddenly spotting Vayne and shouting the warning in Portuguese with real panic in his voice. The delivery gets louder and more frantic as the realisation hits, turning a normal League of Legends callout into an exaggerated alarm. Because Vayne is known for shredding targets late game, the fear feels instantly understandable to anyone who plays the game. The humour comes from the overreaction, which makes a routine enemy sighting sound like an emergency and primes viewers for a fight, a chase or a sudden death.