The line comes from The Simpsons, the long running animated comedy created by Matt Groening that began in 1989, with Homer Simpson voiced by Dan Castellaneta. Homer is known for overreacting to minor setbacks at home and at the Springfield Nuclear Power Plant, and this fed up declaration fits his character perfectly. As short Simpsons clips spread through meme pages, forums and soundboards, this exit line became a reusable reaction alongside other Homer Simpson clips, and it remains popular because walking away from frustration is a situation almost everyone recognises instantly online.