The line comes from the 2005 drama Hustle & Flow, where Terrence Howard plays DJay, a Memphis pimp trying to become a rapper. Mayne is local slang for man, and Howard's drawn out delivery turned a simple greeting into the character's calling card. Clips circulated online as a reaction and entrance sound, detached from the film but keeping the same meaning of a casual, confident check in. It remains popular because the phrase works out of context and is instantly tied to DJay.