The meme comes from CSI: Miami, the television crime drama that premiered in 2002. It is closely associated with David Caruso's character Horatio Caine and the show's signature cut into the opening theme after a one-liner. Online, that structure became widely remixed into reaction videos, short comedy edits, and compilations of cheesy punchlines. Its staying power comes from how instantly recognizable the setup is: a dead-serious delivery followed by an exaggerated musical sting that turns even weak jokes into a punchline.