Giggity is the catchphrase of Glenn Quagmire, the sex-obsessed neighbour in the animated sitcom Family Guy, which first aired in 1999 and was created by Seth MacFarlane. Quagmire uses the word as a leering reaction whenever he sees something he desires, and the distinctive delivery helped turn a single joke into a running gag across the series. As Family Guy clips spread on YouTube and later TikTok, the short sound became shorthand for flirtatious excitement, making it easy to reuse in edits, reaction videos and memes without needing the original scene.