Place this clip right after the reveal shot, then follow it with an oh my god wow reaction for the group response. For grosser discoveries, swap that second beat for an eww brother eww reply, keeping this question as the opening beat of the sequence.
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This is a 5.7-second voice clip of the Spanish phrase 'que es eso' stretched into 'que es esooooooo,' with the final word dragged out for comic effect. It gives a listener a mix of genuine confusion and amused disbelief, the feeling of staring at something so strange you have to say it out loud slowly.