RuPaul, the drag icon and host of RuPaul's Drag Race, is known for quick, cutting one-liners, and 'Who cares?' fits that style perfectly. The clip circulated as an instant button and soundboard favourite, where users could trigger the dismissal with a single tap during streams, chats and edits. From there it spread into TikTok replies, reaction videos and meme edits as a shorthand for unbothered confidence. It endures because the line is universally understood: no context is needed to know that the speaker has already moved on.