Place it at the climax of a fail or jumpscare edit, after a Dun Dun Dun build-up, then follow it immediately with a Vine Boom to close the moment with a joke.
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This clip is a single loud human scream that builds and holds for about thirteen seconds, with a raw, strained voice and no music or other effects behind it. It feels startling and over the top, like someone letting out everything at once, which makes it funny in a group chat and jarring when it catches you off guard.