Place this clip right after the mistake lands in your edit, as the reaction beat before moving on. Build up with No No Wait Wait when the fail is coming, then follow this one with the Faaaa Meme Sound Button for a second, bigger reaction from a different voice.
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The clip is a single human voice stretching out a loud 'gnaaa' groan for about three seconds, recorded like a quick voice memo with no music or other sounds behind it. It lands as exasperated and fed up, the noise someone makes when they are annoyed, stuck, or done trying to explain themselves.