Place it near the end of a short edit, right after the confusing moment it answers, then follow it with Bruh for a deadpan reaction and Goofy Ahh Sounds for a sillier follow-up. Keep the sequence short so the reaction stays the focus and the edit does not lose its pace.
このサウンドについて
Oe Zaikoo is a short meme sound lasting about twelve and a half seconds, built around the phrase in its title. The clip has a playful, offbeat energy that makes it feel like an inside joke dropped at exactly the wrong moment, which is why it works as a quick reaction.