Put it at the very end of a fail clip as the final reaction, then follow it with a baby laughing meme for a second wave, or switch to a cat laugh meme when the joke turns stranger and needs another reaction in the edit.
このサウンドについて
This is a short clip of Patrick Star's big, wheezy laugh, lasting just over three seconds, with his voice rising and falling in a loose, uneven burst. It feels silly, warm and instantly contagious, like hearing a friend lose it over something small. The laugh comes from SpongeBob SquarePants, where he is the pink starfish best friend.