Place it at the end of a rambling rant as the payoff, then cut straight to a shocked reaction to show everyone's stunned faces. For a longer argument, open with a goofy yell to set up the noise before this clip shuts it down.
このサウンドについて
This roughly 30-second spoken clip delivers the blunt shut-your-big-ass-up line in a direct, confrontational voice aimed at someone who will not stop talking. It feels rude, funny and satisfying in the moment, like finally saying out loud what everyone else is thinking, and it lands best as a sharp comeback rather than a gentle joke.