The line comes from Left 4 Dead 2, released by Valve in 2009, where Ellis is one of the four playable survivors fighting through infected hordes. It is one of his contextual voice responses, triggered when another player shoots him, turning a common co-op mistake into character comedy. As clips and soundboards shared short game voice lines online, this reaction survived outside the game because the wording is plain, the delivery is expressive, and it fits almost any moment where someone crosses a line.