This scream comes from Mortal Kombat 9, the 2011 fighting game from NetherRealm Studios, where Kitana, the Edenian princess and fan-wielding fighter, cries out when she is defeated. Short defeat cries like this became popular on soundboards because they are instantly recognisable to fighting game fans and easy to drop into edits. The clip has since spread through gaming montages, reaction videos, and meme edits, where it is used as shorthand for a total loss rather than just a hit.