Place it at the end of an awkward exchange, after the setup has already made the mistake clear. Follow it with a Vine Boom for a heavier punch, or put an Anime Wow just before it so the surprise builds into it.
Over dit geluid
This is a 43-second vocal clip built around one long, drawn-out ehhh, followed by shorter eh eh eh bursts from the same voice. The stretched groan and the clipped repeats make it sound exasperated, awkward and a little mocking, like a reaction to something too silly to answer properly.