Place it near the end of an edit, after the setup has already made the disappointment clear. Follow it with Emotional Damage for a bigger reaction, or lead into it with Sad Meow Song so the disappointment builds before the main moment arrives.
Over dit geluid
This is a Russian sad meme clip lasting about 18 seconds, built around the theme of sad faces and a heavy, gloomy mood. It feels weary and downcast, like a slow sigh after bad news, and it lands best when someone wants sympathy rather than a laugh. The crying-face mood is the whole point, turning a small disappointment into something deliberately over-the-top and miserable.