Usopp is the cowardly but loyal sniper of the Straw Hat Pirates in One Piece, the long-running manga and anime created by Eiichiro Oda. Miskine comes from Arabic and is common slang in French-speaking communities for calling someone pitiable in a teasing way. Fans combine the two in edits and soundboards to mock Usopp's frequent panic, lies and misfortune. The phrase spread through anime meme pages and short video edits, where a single pitying line works as a quick punchline without needing context from a full episode.